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ProFound Therapeutics: Cardiovascular, Metabolic & Neuroscience Co-Op
Flagship Pioneering · Co-Ops & Internships
- Where
- Cambridge, MA USA
- Posted
- Sep 16
ProFound Therapeutics is seeking an innovative and highly motivated Co-Op with experience in cell biology and/or disease biology to play a vital role in the company’s Cardiovascular, Metabolic & Neuroscience team. Under the supervision of senior scientists on the Cardiovascular, Metabolic & Neuroscience team, this individual will receive structured training and hands-on experience in in vitro cell-based assays supporting ongoing mid- and high-throughput functional projects. This individual will contribute scientific and technical expertise to a multidisciplinary team, emphasizing conceptualization, experimentation, data analysis, presentation, and strategic planning. The ideal candidate for this position will have coursework or early research experience in cell biology, physiology, or a related discipline and be enthusiastic and capable of working in a multidisciplinary (e.g.
What you'd do
- Serve as a contributor to the Cardiovascular, Metabolic & Neuroscience team, whose mission is to discover new therapeutics and validate new therapeutic targets
- Collaborate with senior scientists to support ongoing cardiovascular, metabolic, and neuroscience projects
- Culture, differentiate, and maintain human primary cells and cell lines (e.g. adipocytes, endothelial cells/HUVECs, hepatocytes, and skeletal muscle cells)
- Assist with the development and testing of functional assays using human primary cells for low-, mid-, and high-throughput applications via high-content imaging and confocal immunofluorescence (IF)
- Support disease-relevant readouts, including mitochondrial function, endothelial barrier/permeability, glucose uptake, and lipolysis
- Prepare reagents for functional assays and screens, including peptide reconstitution and aliquoting
- Analyze, interpret, and present experimental data (e.g. GraphPad Prism, Excel) at team meetings and in reports
- Organize and maintain experimental records in Benchling for review
- Report experimental plans and results to the scientific team
- Proactively review literature to contribute to new ideas and methods/technologies for discovery and therapeutic areas
What they want
- Pursuing a Bachelor’s or Master’s degree in cell biology, biology, physiology, biochemistry, or a related field
- Coursework or hands-on research experience in mammalian cell culture and basic laboratory techniques, and attention to detail
- Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner
- Strong collaborative skills with evidence of working in a team
What you get
- Build alongside founders. You’ll work inside the same hypothesis-driven process Flagship uses to conceive and launch first-in-category companies.
- This can be the start of a longer story. Strong co-ops are considered for future opportunities across Flagship and its portfolio companies, not just for this one role.
- Work alongside people who left the safe path. Your colleagues are scientists, engineers, and operators who chose to build something new rather than join something already established.
- Take on real ownership. You're contributing to ventures that are still being defined. Your work can shape real decisions, not just support them.
- Be paid like the contributor you are. Compensation reflects the real work you take on.
About Flagship Pioneering · Co-Ops & Internships
ProFound Therapeutics Inc. is a privately held, early-stage biotechnology company with the vision to revolutionize the human therapeutic landscape. ProFound has recently made the news by being included in the Fierce Biotech’s list of the hottest Biotech companies. ProFound Therapeutics Inc. was founded by Flagship Pioneering, a team of entrepreneurial scientists that conceives, creates, resources, and grows first-in-category life sciences companies.