Internship

Metaphore Biotechnologies: Analytical Characterization / Protein Science Co-Op

Flagship Pioneering · Co-Ops & Internships

Where: Cambridge, MA USA
Posted: Sep 21

This position is open exclusively to current Northeastern University Co-Op students.

Work Period: January 2027 to June 2027. This is a full - time, 40 hours per week position with 5 days in office.

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

What you'd do

Develop and optimize analytical assays to support multiple company programs.
Execute and analyze data from a suite of analytical assays, including QC (purity, sizing, thermostability by SEC, DLS, nanoDSF) and kinetics/affinity assessments using Octet BLI.
Contribute to the development and implementation of UPLC-based separation methods, including Reversed Phase, Hydrophobic Interaction Chromatography, and Ion-Exchange Chromatography.
Draft and update protocols, SOPs, and Benchling templates.
Research and develop additional methods as needed for developability assessments such as AC-SINS, ELISA, and Poly-reactivity.
Pursuing a degree in Biochemistry, Biology, Chemistry, Bioengineering, or a related field.
Demonstrated critical thinking and proactive problem-solving skills.
Interest in protein science with the ability to think both deeply and broadly about proteins.
Curiosity-driven with a strong desire to learn and ask questions.
Attention to details and strong organizational skills for careful documentation and tracking of experiments.

What you get

Build alongside founders. You’ll work inside the same hypothesis-driven process Flagship uses to conceive and launch first-in-category companies.
This can be the start of a longer story. Strong co-ops are considered for future opportunities across Flagship and its portfolio companies, not just for this one role.
Work alongside people who left the safe path. Your colleagues are scientists, engineers, and operators who chose to build something new rather than join something already established.
Take on real ownership. You're contributing to ventures that are still being defined. Your work can shape real decisions, not just support them.
Be paid like the contributor you are. Compensation reflects the real work you take on.

About Flagship Pioneering · Co-Ops & Internships

Metaphore Biotechnologies is harnessing the power of mimicry to make previously intractable drug targets accessible and unlock breakthroughs that outperform today's drugs for maximum patient impact. The company's MIMiC™ platform is a computationally driven bioplatform designing new therapeutics where function, specificity, and selectivity are programmable. Metaphore Biotechnologies was founded by Flagship Pioneering's venture creation engine, which has also given rise to companies such as Moder…